How aseptic manufacturing actually works
A look inside the cleanrooms where biologics are made, and why the margin for error is effectively zero.
How aseptic manufacturing actually works
A look inside the cleanrooms where biologics are made, and why the margin for error is effectively zero.
Read →What 440 days on a bicycle taught me about discomfort
Somewhere in Central Asia I stopped dreading hard days. Here is what changed.
Why smart people stay in the wrong rooms
On the pull of familiarity, sunk cost thinking, and why changing direction takes more than a decision.
The quiet cost of always being available
We optimised for response time and lost something harder to name. A note on attention, availability, and what we give away when we stay connected.
What silence taught me in the Pamir mountains
Three weeks at altitude with no signal and no agenda. What happens when the noise stops and there is nothing left to distract you from yourself.
The Silk Road was never just about trade
Cycling through the same valleys that connected Rome to China, I kept thinking: the movement of ideas was always more consequential than the movement of goods.
Looking up from a tent in Kazakhstan
When you sleep outside for months, the sky stops being a backdrop. On dark skies, light pollution, and why most people have never seen the Milky Way.
The cell is not a machine. It is a city.
We keep using engineering metaphors to describe biology and keep getting surprised when they break down. A different way of thinking about living systems.
Why drug pricing makes no economic sense — and why it persists
Healthcare markets break every assumption classical economics makes. Understanding why helps explain why fixing them is so much harder than it looks.
Regulation as design: what pharma can teach other industries
The most regulated industry in the world has also produced some of the most consequential innovations. That is not a coincidence.